Harvi by PVLoops

Harvi Advanced

Harvi-Advanced is intended for students, fellows and postgraduates interested to take a deeper dive into cardiovascular physiology and the hemodynamics of disease and therapeutics. This version includes two textbooks (with additional textbooks in development) and an extensive cardiovascular simulation with the ability to simulate a multitude of common disease states and introduce various therapies, including mechanical support devices.

Watch the Intro Video

$60 / year

This license provides access to:

Two completed comprehensive textbooks on the basics of cardiovascular physiology, the Student textbook and access to 2 additional advanced books (covering the hemodynamics of common cardiac conditions and mechanical circulatory support) as they become available
Advanced cardiovascular simulation with ability to simulate all forms of heart failure, valve diseases, coronary artery disease, understand myocardial energetics and introduce and vary settings of a variety of mechanical support devices and basic set of intravenous pharmacologic agents
Extensive Try-It- Now libraries
Access a library of prestored clinical cases and examples
The Patient Simulator
Ability to save, recall and share parameter sets that you create

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Features

Textbooks

Part I of the Harvi-Advanced textbook has detailed chapters on

Left ventricular (LV) pressure-volume loops
Preload
Afterload
Contractility
Diastolic Properties
Ventricular-vascular interactions
Right ventricular and atrial pressure-volume loops
Means of assessing pressure-volume loops (invasive and noninvasive)
A Try-it-Now library that illustrate the concepts in each of these chapters.

Part II of the Harvi-Advanced textbook has detailed chapters on

Normal Valve Function and Flow Patterns
The Pericardium and Ventricular Interactions
Excitation-Contraction Coupling
Determinants of Myocardial Oxygen Consumption
Basics of Myocardial Metabolism
Regulation of Coronary Blood Flow
Basics of Cardiovascular Receptor Biology and Pharmacology
Autonomic Control of the Circulation
Exercise Physiology
A Try-it- Now library that illustrate the concepts in each of these chapters

Parts III and IV of the Harvi-Advanced textbook series (in development) will cover

Cardiovascular pathologies and the hemodynamics
Mechanical circulatory support

Simulation Parameters

The Harvi-Advanced simulation gives access to

Vary detailed properties of the ventricles, atrial and vascular systems
Introduce and vary severity of valve pathologies
Introduce and vary severity of common shunts (ASD, VSD, PDA)
Introduce and vary left main coronary artery stenosis and learn about coronary autoregulation and the balance between ventricular energy supply and demand
Introduce and vary pericardial constraints and effusions
Alter the heart rhythm (PACs, VT, AFib)
Introduce and vary doses of some frequently used drugs
The Patient Simulator, which will adjust simulation parameter values to match a specified hemodynamic profile

Simulation Outputs

Graphical output options include ability to display

LV pressure-volume loops
Pressure-volume loops of 2 or 4 chambers simultaneously
A wide range of continuous signal tracings over time (e.g., blood pressure, pulmonary pressures, blood flow profiles across any cardiac valve, LV and RV pressures and volumes, blood flow profile through
1, 2 or 3 time plots simultaneously
Real-time display of myocardial oxygen consumption and ventricular work
Pressure-flow characteristics of different forms of mechanical circulatory support

Numerical output options include ability to display

A wide ranges of standard cardiovascular parameters (e.g., blood pressure, pulmonary pressures, cardiac output, LV and RV ejection fractions, volumes and pressures)
Cardiac valve characteristics (regurgitant fractions, valve areas, mean and peak pressure gradients)
Flows through shunts and Qp:Qs values
Mechanical support device flows

Compare Versions of Harvi

Click on a category to see what is included in each version.

Books

Student
Advanced
ECMO
Complete
Professor

Basic Physiological Principles
no
x
no
x
x

Advanced Physiological Principles
no
x
no
x
x

Student - Introduction to Cardiovascular Physiology
x
x
x
x
x

ECMO and the Physiology of Gas Exchange
no
no
x
x
x

Understanding Blood Gases
x
x
no
x
x

Input Panels

Student
Advanced
ECMO
Complete
Professor

Basic LV
x
x
no
x
x

Basic 4 Chamber
x
x
x
x
x

Ventricles & Pericardium
no
x
no
x
x

Atria
no
x
no
x
x

Valves & Shunts
no
x
x
x
x

Rhythm
no
x
no
x
x

Vessels
no
x
no
x
x

Patient Simulator
no
x
x
x
x

Pharmacology
x
x
x
x
x

Devices
no
x
x
x
x

ECMO
no
no
x
x
x

CardioPulmonary Patient
no
no
x
x
x

ECMO/Patient
no
no
x
x
x

Lung/MVO2/ABG
no
no
no
no
x

IABP
no
x
no
x
x

Scenarios
no
no
no
no
x

CardioPulmonaryBypass
no
no
x
x
x

TEACH
no
x
x
x
x

Output Panels

Student
Advanced
ECMO
Complete
Professor

Basic
x
x
x
x
x

Hemodynamics
x
x
x
x
x

Valves/Shunts
no
x
no
x
x

Aortic Valve Doppler
no
x
no
x
x

Pulmonary Valve Doppler
no
x
no
x
x

Devices
no
x
no
x
x

Blood Gases
no
no
x
x
x

LV Metabolism
no
x
no
x
x

ECMO
no
no
x
x
x

Capture/Hemo
x
x
x
x
x

Capture/ABG
no
no
x
x
x

Plots

Student
Advanced
ECMO
Complete
Professor

1 PV Loop & 1 Time Plot
x
x
x
x
x

1 PV Loop & 2 Time Plots
no
x
x
x
x

1 PV Loop & 3 Time Plots
no
x
no
x
x

4 PV Loops & 3 Time Plots
x
x
no
x
x

2 PV Loops
no
no
no
no
x

2 PV Loops & 2 Time Plots
no
no
x
x
x

4 PV Loops
no
no
no
no
x

6 Time Plots
no
no
no
no
x

Patient Monitor
x
x
x
x
x

Patient Monitor & 1 PV Loop & 1 Time Plot
no
x
no
x
x

Energetics (MVO2-PVA)
no
x
no
x
x

Blood Gases
no
no
x
x
x

Blood Gases & 1 PV Loop & 1 Time Plot
no
no
x
x
x

Blood Gases & 4 PV Loops & 4 Time Plots
no
no
x
x
x

Body
no
no
x
x
x

Body & 1 PV Loop & 1 Time Plot
no
no
x
x
x

Body & 4 PV Loops & 3 Time Plots
no
no
x
x
x

Pump Hemodynamics
no
x
no
x
x

ECMO Monitor
no
no
x
x
x

PV Loop & ECMO Monitor & Patient Monitor
no
no
x
x
x

Body & ECMO Monitor & Patient Monitor
no
no
x
x
x

ABG & ECMO Monitor & Patient Monitor
no
no
x
x
x

CardioPulmonary Bypass
no
no
no
no
x

CardioPulmonary Bypass & 4 PV Loops & 4 Time Plots
no
no
no
no
x

CardioPulmonary Bypass & Blood Gases
no
no
no
no
x

CardioPulmonary Bypass & Patient Monitor
no
no
x
x
x

CardioPulmonary Bypass & 4 PV Loops & 1 Time Plot & Blood Gases
no
no
no
no
x

Display and Download Tools

Student
Advanced
ECMO
Complete
Professor

Signal Recording
no
no
no
no
x

End of Beat Input & Output Recording
no
no
no
no
x

Auxiliary Plot Windows
no
no
no
no
x